Skin
How skin changes after 40, and the evidence behind tretinoin, topical estriol, azelaic acid and copper peptides.
5 articles

SkinEstriol cream for the face: what the small studies show, and who should avoid itWhat small trials of estriol and estrogen cream on facial skin found, whether it reaches your bloodstream, who should avoid estrogen, and what compounded means.7 min read
SkinCopper peptide (GHK-Cu) skin benefits: what is known, and what is notWhat the copper peptide GHK-Cu is, what lab and small human studies found for aging skin, why the evidence is thin, and what is still unknown about it.6 min read
SkinMenopause skin changes: collagen loss, dryness, and what actually has evidenceWhy skin gets thinner and drier after menopause, what studies found about collagen loss, and which treatments, from sunscreen to tretinoin, have evidence.7 min read
SkinTretinoin for wrinkles: what the FDA label and trials actually showWhat FDA-approved tretinoin cream is labeled to do for wrinkles, what trials measured, how to handle the irritation, and why it is not for use in pregnancy.7 min read
Other topics
TreatmentsHow each hormone treatment works, how it is used, and what to ask your clinician.12 articles →
GLP-1sWhat GLP-1 medicines do to your body beyond the scale, and how to protect your strength.7 articles →
SymptomsWhat hormone therapy can and cannot do for the changes you are noticing.7 articles →
Sexual & urogenital healthVaginal dryness, discomfort and urinary changes after menopause, and the local treatments used for them.5 articles →
Safety & costSide effects, risks and what hormone therapy costs, laid out with the research behind them.10 articles →
Energy & recoveryVitamin injections, NAD+, glutathione and sermorelin: what each one is, and what the research does and does not show.5 articles →
HairThinning hair in midlife, and what topical minoxidil and its companions can and cannot do.4 articles →